Background. Spontaneous coronary artery dissection (SCAD) is a rare cause of acute coronary syndrome (ACS). Aortic dissection\nand SCAD share common aetiologies such as a fibromuscular dysplasia (FMD), Marfan, Ehlers Danlos, and more rarely systemic\nlupus erythematosus and Loeys-Dietz; however, SCAD has never been known to have a familial association with aortic dissection.\nCase Summary. This case report describes a 48-year-old woman suffering from SCAD who had a mother who died from ascending\naortic dissection in her 50s. Discussion. This is the first case report to our knowledge of a patient with SCAD with a first-degree\nrelative with aortic dissection. Our case is interesting in that it shows that if predisposition to arterial dissection was inherited\nfrom mother to daughter, one of them suffered an extremely rare manifestation of their underlying disease. It also shows that a\nhigh index of suspicion is needed for SCAD in the presence of a patient with ACS and a family history of dissection elsewhere\nin the arterial tree.
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